bottom-up and top-down methods of synthesis – article1000.com
The top-down approach often uses the traditional workshop or microfabrication methodsin whichexternally-controlled tools are used to cut, mill and shape materials into the desired shape and order.Attrition and milling for making nano particles are typical top-down processes. Bottom-up approaches, in contrast, arrange molecular components themselves into some useful conformation using the concept …
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